Laboratory Listing

Name: Timothy A. Miller
Laboratory: Plastic Surgery laboratory
Lab Location: Greater Los Angeles VA Health Care Center at West Los Angeles, Building 114, Room 221, 11301 Wilshire Blvd., Los Angeles, CA 90073. Phone: (310) 268-3060, Email: millerlab@hotmail.com
Lab facilities: Facilities include the Animal Biology Section laboratory, the Molecular Biology Section Laboratory and the Bone Cell Physiology Laboratory, housed in buldings 113 and 114. Together, these laboratories provide over 2000 square feet of research space. The labs are fully equipped for cell culture and molecular biology experiments, epifluorescent microscopy, and computer image analysis. Adjacent VA Core facilities include FACS analysis and histology; a fully accredited animal research facility is housed in building 113. UCLA core facilities are also available, including Microarray analysis.

Animal Facilities: Yes
Type: Animal studies currently include mice, rats and rabbits.

Type of research: Cell culture, animal models and molecular biology. Currently, the lab is focused on studies using rhBMP-2 produced in bacterial expression systems, in an effort to develop bone graft substitute.

Funding: VA Merit Review

Research Fellowship Available: Yes
Investigator's Name: Timothy A. Miller, MD, Professor, UCLA Div. of Plastic Surgery.
Project Title: Molecular Mechanism of Bone Regeneration: Role of BMP-2
Brief Description: We have a long-standing interest in the development of bone-graft substitutes. Currently, we are investigating the use of bacterial expression systems for the production of rhBMP-2. Efficacy is being tested in cell culture and animal models. Molecular mechanisms are bring evaluated using Microarrays.

Opportunity for student degree program: No

Funding available from supervisor
PARTIAL funding available. Student must obtain additional funding.

Other requirements (i.e. background, MD degree, etc.) Please specify: Prefer prior cell culture/molecular biology experience.

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